The standards for quantitative risk assessment in China are introduced. Taking a high-sulfur natural gas conditioning plant in northeastern Sichuan as an example, Quantitative risk assessment is conducted using the national standard 《Determination method of external safety distance for hazardous chemicals production units and storage installations》(GB/T 37243-2019) and 《Risk criteria for hazardous chemicals production unit storage installations 》(GB36894-2018). The determination basis of key parameters is explained, and the problems and suggestions in the quantitative risk assessment of high-sulfur natural gas conditioning plant in practical applications are proposed.